Job Posting

Scientist I, Preclinical Research

About us

Ray Therapeutics is developing novel optogenetics gene therapies for patients with blinding diseases. The company is developing its lead candidate RTx-015 in retinitis pigmentosa, a degenerative retinal disease with significant unmet medical need. The company’s mission is to use optogenetics to restore vision, independent of genetic mutation for patients with inherited retinal diseases. Ray Therapeutics is based in the San Francisco Bay Area. For additional information, please visit our About Us page.

Position Summary:

We are seeking an exceptional scientist to join our growing team. This office-based position is located in Berkeley, California. We are looking for curious, passionate, and motivated individuals to contribute to the development of our next-generation Optogenetics-based gene therapy platform.

Essential Duties and Responsibilities:

  • Design and execute experiments, offering creative solutions to complex problems; ability to work independently and think innovatively.
  • Optimize and oversee AAV production, including upstream growth, downstream purification, and assay execution (titering, quality control).
  • Provide molecular and cell biology support to execute standard cell culture processes, including transfection, transduction, selection, sub-cloning, clonal expansion, and banking, as well as cell model characterization.
  • Design and conduct in vitro cell-based and potency assays to support gene therapy research projects.
  • Collaborate in a laboratory setting to explore, develop, and validate novel models for inherited retinal diseases (IRD) and neurological disorders.
  • Identify, evaluate, and implement novel methods or technologies to enhance workflow efficiencies and improve the quality of cell model deliverables.

Qualifications and Experience:

  • PhD degree in a relevant discipline.
  • Biotech industry experience is a plus.
  • Exposure to AAV production, purification, and analytical methods.
  • Hands-on experience in biochemistry techniques, including (but not limited to) qPCR, dPCR, ddPCR, western blot, immunoassays, FACs analysis, protein assay development and data analysis.
  • Familiarity with multiwell plate assays (e.g., 96 well plate AAV transduction of mammalian cells and imaging readout).
  • Experience in developing new biochemical and cell-based/potency assays.
  • Demonstrated ability to multitask and maintain high productivity in a multidisciplinary, fast-paced environment.
  • Ability to work independently and collaboratively, including training other team members.
  • Strong communication, problem-solving, and analytical skills.

Working Conditions:

  • Prolonged periods of being at a stationary desk, work computer, or lab bench.
  • Ability to occasionally adjust, handle, or move objects up to 50 pounds.
  • Ability to assess the accuracy, neatness, and/or thoroughness of the work assigned.
  • Ability to communicate with others to exchange information.

Ray Therapeutics does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity or expression, national origin, age, disability, veteran status, marital status, or based on an individual’s status in any group or class protected by applicable federal, state, and local law. We invite applications from minorities, women, the disabled, protected veterans and all other qualified applicants.

Ray Therapeutics offers a competitive total rewards package that includes a market competitive base salary, target bonus, and equity in addition to health care benefits.

Please submit please submit your resume and cover letter to: careers@raytherapeutics.com